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One thing thatвЂ™s key is that you have to exclude other causes. How do you make the decision, if they are feeling terrible two months after getting Covid, if what you think they have is long Covid or just possibly something else, another virus, theyвЂ™ve developed a chronic ailment they would have developed anyway? Given how many ways this can present, how do you make the judgment as a clinician if somebody fits in your clinic, or theyвЂ™ve just gotten sick sometime after they had Covid? lekshmi santhosh So there is such a huge range of symptoms here. So cognitive impacts, mental health impacts, headaches, difficulties with concentrating, neuropathies, different sensation in the nerves, these have all been seen after Covid. Some people tend to have neurological symptoms, that cognitive impairment thatвЂ™s been colloquially called вЂњbrain fog,вЂќ and some people argue that using that term actually diminishes the severity of what people are experiencing. Some people clearly have a more cardiopulmonary phenotype with a lot of shortness of breath, wheezing, coughing, chest pain after Covid. And I think thatвЂ™s one point that I make all the time to patients and other providers, is that there is no one long Covid experience. One thing that we know for sure is that some people will have different what we call phenotypes of long Covid. So itвЂ™s not surprising that some people have acute impacts in multiple organ systems and some people have chronic impacts in multiple organ systems. But it really can be a disease of the whole body, acutely - in the short term - as well as chronically. Covid is not just a disease of the lungs - even though as a pulmonologist, a lung doctor, of course, I love the lungs.

I think that list matches a lot of the medical literature out there right now. If you were to list every symptom you believe is credibly associated with long Covid, what would that list include? lekshmi santhosh Santhosh helps me here wade through what we know and - frustratingly, but really importantly - what we donвЂ™t know about long Covid, what itвЂ™s doing to us, and what we can do about it.ДЄs always, my email - if you have feedback, guest suggestions, recommendations of things we should read or think about - is Lekshmi Santhosh, thank you so much for being on the show. That clinic opened in May 2020 and was one of the first to focus on treating long Covid patients specifically. Medical Center, and sheвЂ™s a founder and medical director of U.C.S.F.вЂs Long Covid and Post-I.C.U. Lekshmi Santhosh is an assistant professor of pulmonary and critical care medicine at U.C.S.F.

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And, of course, weвЂ™re still trying to figure out how to treat it.Дr. WeвЂ™re still trying to understand the cause or the causes. Others cast doubt on the whole phenomenon. Some studies make it seem unbelievably widespread. WeвЂ™ve known long Covid is a thing for years now, but to try to dive into the literature here is to realize very quickly how little we actually know.Дifferent studies give wildly different estimates of who gets it, how often and why. This one term may be hiding a lot of different conditions, maybe even a lot of different causes. ItвЂ™s this one term for this vast range of experiences of symptoms, of outcomes. For others, it can be life-altering - debilitating brain fog, constant exhaustion, cardiovascular problems, blood clotting. For some people, thatвЂ™s going to be modest - a cough, some fatigue. You can find the listing at /careers, and there will be a link in the description for this episode.Д«ut for today, depending on the data you look at, between 10 percent and 40 percent of people who get Covid will still have inexplicable symptoms months later. And weвЂ™re going to be closing the position in two weeks, so nowвЂ™s the time to apply. Location-wise, New York is preferred, but weвЂ™re open to remote work. This is going to be someone who gets the show deeply, who is both broad and obsessive in their interests, and who can read and synthesize and communicate a lot of information fast.

This is вЂњThe Ezra Klein Show.вЂќД«efore we begin today, weвЂ™re looking for a researcher to join the show. Lekshmi Santhosh parses what research has illuminated about Long Covid, and what questions remain.

Transcript What We Do - and, Frustratingly, DonвЂ™t - Know About Long Covid Dr.

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